circad | circRNAs associated with diseases

circ6229/hsa_circ_0000523
Gene	METTL3	Organism	Human
Genome Locus	chr14:21971315-21972024:-	Build	hg19
Disease	Colorectal Cancer	ICD-10	Malignant neoplasm of rectosigmoid junction (C19)
DBLink	Link to database	PMID	25624062
Experimental Method
Sample Type	Tissue and CRC Cell lines	Comparison	Tumour tissues and matched normal colon mucosa from 31 Colorectal Cancer patients
Method for Estimation	Quantitative PCR	PCR Details	Detailed Experimental Procedure
Primers (Experimented)	Forward CGGAAGGTTGGAGACAATGC Reverse GTCCACTAAGGAACAACAGAGCAA	Statistics	Fold Change : Downregulated pvalue : p<0.05
Citation
Bachmayr-Heyda, A, Reiner, AT, Auer, K, Sukhbaatar, N, Aust, S, Bachleitner-Hofmann, T, Mesteri, I, Grunt, TW, Zeillinger, R, Pils, D (2015). Correlation of circular RNA abundance with proliferation--exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis, and normal human tissues. Sci Rep, 5:8057.